How does Tamoxifen work?

Uses: Gynecomastia, cancer hormone therapy, female infertility, breast cancer treatment, breast cancer prevention

How does Tamoxifen work?
Tamoxifen is an anti-estrogen that blocks the action of estrogen in the body to treat disorders related to hormonal disorders. Tamoxifen is used in the prevention and treatment of breast cancer, as well as in the treatment of anovulatory infertility and the prevention of breast development in male patients due to drug use.

How to use Tamoxifen and adjust the dose?
Tamoxifen is an oral medication that can be taken on an empty or full stomach.

Breast cancer treatment
Take 20 mg daily.

Preventing Breast Cancer in High-Risk Women
Take 20 mg daily for five years.

Ovulatory Infertility
Take 20 mg daily on days 2, 3, 4 and 5 of the menstrual cycle. If necessary, increase the dose to 40 mg per day and then 80 mg per day in subsequent menstrual cycles. For women with irregular menstrual periods, treatment can be started any day and repeated after forty-five days, or on the second day of the next menstrual period.

Gynecomastia (due to antiandrogen drugs)
Take 20 mg once a week.

What are the side effects of Tamoxifen?
Common side effects of tamoxifen include dizziness, fatigue, vision problems, headache, nausea, vomiting, diarrhea, constipation, changes in taste, muscle or joint pain, hot flashes, and hair loss.

Who should not use Tamoxifen?
Those who are allergic to tamoxifen or any component of its preparations
People who have had or are currently suffering from deep vein thrombosis or pulmonary embolism
People taking Anastrozole

Pharmacist Tip:
This drug may cause vision problems, so avoid driving a car or operating machinery until you know its effects.
You will need regular blood tests, liver function tests, breast exams, and eye exams while you are taking this medicine. Your doctor may perform other tests for you.
Pregnancy should be avoided during treatment and for at least two months after the last dose. Use effective non-hormonal contraception, such as condoms, when needed.
Do not reduce your dose or stop the medication on your own, even if you may not be feeling unwell.
Tell your doctor right away if you have menstrual irregularities, unusual vaginal bleeding, or pelvic pain while using this medication.

Common taking time:
It is usually taken once a day. Try to take the medicine at the same time each day.

The information is for reference only, and the actual medication time will be adjusted according to individual circumstances.

Common possible conflicting drugs:
Antidepressants, such as bupropion (Bupropion), fluoxetine (Fluoxetine), paroxetine (Paroxetine)
Other cancer drugs, such as Aminoglutethimide, Letrozole

Tamoxifen may counteract with multiple medications. If you are taking the above medicines, please inform your doctor or pharmacist, the dosage may need to be adjusted.


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