How does Leuprorelin work?


How does Leuprorelin work?
Leuprolide is a gonadotropin-releasing hormone agonist. It balances hormones in the body and treats problems caused by hormonal imbalances.

Leuprolide is used to treat breast cancer, advanced prostate cancer, endometriosis, uterine fibroids, and precocious puberty (premature puberty in young children).

How to use Leuprorelin and adjust the dose?
Your healthcare provider will give leuprolide either intramuscularly or subcutaneously. The usual dose is 11.25 mg every three months or 2.75 mg every month. Allow your doctor to determine the dosage and frequency of medication needed depending on the condition.

Palliative care for advanced prostate cancer
3.75 mg every month or 11.25 mg every three months.

3.75 mg every month or 11.25 mg every three months for a maximum of six months with no repeat courses. Begin treatment on the first five days of the menstrual cycle.

Uterine fibroids
3.75 mg every month or 11.25 mg every three months for up to six months. Begin treatment on the first five days of the menstrual cycle. The course of treatment usually takes three months.

Central precocious puberty
Injection every four weeks. Drugs should be stopped by age 11 for girls and 12 for boys.

What are the side effects of Leuprorelin?
Common side effects of leuprolide include headache, dizziness, nausea, stomach upset, weight gain, hot flashes, trouble sleeping, muscle or back aches, breast pain, sweating, acne or pimples, and pain and redness at the injection site.

Who should not use Leuprorelin?
Those who are allergic to leuprolide or any component of its preparation
Those who are allergic to gonadotropin-releasing hormone and its derivatives
People with abnormal vaginal bleeding
men with severe osteoporosis
Pregnant Women / Breastfeeding Women / Family Planning Women

Pharmacist Tip:
You may need regular blood tests.
Tell your doctor right away if you have seizures, a burning sensation in the tumor, chest pain, tightness, or difficulty breathing while using this medicine.
People with diabetes should watch for symptoms of high blood sugar and report any difficulties with blood sugar control to their doctor.

Common taking time:
Your doctor will determine the medication and frequency needed depending on your condition.

Common possible conflicting drugs:
Antiarrhythmic drugs such as Amiodarone, Quinidine, Disopyramide, Sotalol
QT prolongers such as Dronedarone, Amisulpride, Pimozide

If you are taking the above medicines, please inform your doctor or pharmacist, the dosage may need to be adjusted.


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